Brook I Bacteriology and beta-lactamase activity in ear aspirates of acute otitis media that failed amoxicillin therapy. Save Preferences. Privacy Policy Terms of Use. This Issue. Citations 2. View Metrics. Twitter Facebook More LinkedIn. Original Article. September Gober, MD. Back to top Article Information.
Access your subscriptions. Access through your institution. Add or change institution. Free access to newly published articles. Purchase access. Rent article Rent this article from DeepDyve. Access to free article PDF downloads. Save your search. Customize your interests. Create a personal account or sign in to:. Privacy Policy. Amoxicillin is also active against gram-negative bacteria including Haemophilus influenzae , Escherichia coli , Helicobacter pylori , and Neisseria gonorrhoeae. There are not many strong studies that have been performed to show a direct comparison of cefdinir and amoxicillin.
The effectiveness of these antibiotics will depend on which bacteria is causing the infection. Talk to your doctor or healthcare provider about which antibiotic will work best for you.
As generic antibiotics, cefdinir and amoxicillin are widely available. Almost all Medicare Part D and insurance plans will cover cefdinir and amoxicillin. Amoxicillin is available in generic and brand-name versions. The most common side effects associated with cefdinir and amoxicillin are diarrhea, nausea, and vomiting. Amoxicillin is more likely to cause headache when taken with clarithromycin and lansoprazole for H. Amoxicillin may also have a higher incidence of rash after taking it.
More serious side effects of cefdinir and amoxicillin include allergic or hypersensitivity reactions. If you experience adverse events like trouble breathing or severe rash, seek medical attention immediately. This may not be a complete list. Consult your doctor or pharmacist for possible side effects. Cefdinir interacts with antacids as well as iron supplements. Antacids and iron supplements can lower the absorption of cefdinir and decrease its effectiveness. Cefdinir should be taken at least two hours before or after administering these other medications.
Both cefdinir and amoxicillin can interact with anti-gout medications like probenecid and allopurinol. Anti-gout agents can increase the blood levels of cefdinir and amoxicillin, which can lead to increased side effects.
Cefdinir and amoxicillin have been known to cause prolonged prohrombin time in those who are also taking warfarin. This drug interaction can cause an increased risk of bleeding. Antibiotics have been known to decrease the effectiveness of oral contraceptives. Alternate birth control methods may be needed to reduce the risk of pregnancy. This may not be a complete list of all possible drug interactions. Consult a doctor with all the medications you may be taking.
Cefdinir and amoxicillin should be avoided if you have a penicillin allergy. Because these drugs are chemically similar to penicillin, they may cause a severe allergic reaction if you have an established penicillin allergy. Diarrhea is one of the most common side effects of antibiotics like cefdinir and amoxicillin.
These antibiotics can also increase the risk of a more severe type of diarrhea caused by Clostridium difficile. If you have a medical history of C. These antibiotics should only be prescribed for infections caused by bacteria. Cefdinir and amoxicillin are most effective when they are targeting susceptible bacteria.
Save this study. Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U. Federal Government. Read our disclaimer for details. Last Update Posted : May 2, Study Description. This study is a comparison between two commonly used antibiotics Cefdinir vs. The hypothesis is that the two treatments would be at the least equivalent based on clinical outcome measures of improvement in quality of life. Detailed Description:.
Drug Information available for: Amoxicillin Amoxicillin sodium Cefdinir. FDA Resources. Arms and Interventions. Outcome Measures. Secondary Outcome Measures : Clinical signs and symptoms alleviated [ Time Frame: At baseline and within 1 week of completing treatment ].
Eligibility Criteria.
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